Precision oncology for acute myeloid leukemia using a knowledge bank approach

Causative mutations in a patient’s cancer drive its biology and, by extension, its clinical features and treatment response, a concept underpinning the vision of precision medicine. However, considerable between-patient heterogeneity in driver mutations complicates evidence-based personalization of...

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Vydáno v:Nat Genet
Hlavní autoři: Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott, Ultan, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764082/
https://ncbi.nlm.nih.gov/pubmed/28092685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3756
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