ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group

We studied 1696 patients (18 to 61 years) with acute myeloid leukemia for ASXL1 mutations and identified these mutations in 103 (6.1%) patients. ASXL1 mutations were associated with older age (P<0.0001), male sex (P=0.041), secondary acute myeloid leukemia (P<0.0001), and lower values for bone...

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Опубликовано в: :Haematologica
Главные авторы: Paschka, Peter, Schlenk, Richard F., Gaidzik, Verena I., Herzig, Julia K., Aulitzky, Teresa, Bullinger, Lars, Späth, Daniela, Teleanu, Veronika, Kündgen, Andrea, Köhne, Claus-Henning, Brossart, Peter, Held, Gerhard, Horst, Heinz-A., Ringhoffer, Mark, Götze, Katharina, Nachbaur, David, Kindler, Thomas, Heuser, Michael, Thol, Felicitas, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze
Формат: Artigo
Язык:Inglês
Опубликовано: Ferrata Storti Foundation 2015
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349270/
https://ncbi.nlm.nih.gov/pubmed/25596267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.114157
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