Comparison of DNA repair and radiosensitivity of different blood cell populations

por Heylmann, Daniel, Ponath, Viviane, Kindler, Thomas, Kaina, Bernd
Publicado en Sci Rep (2021)

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells

por More, Piyush, Goedtel-Armbrust, Ute, Shah, Viral, Mathaes, Marianne, Kindler, Thomas, Andrade-Navarro, Miguel A., Wojnowski, Leszek
Publicado en Oncotarget (2019)

K-Ras(G12D)–induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to γ-secretase inhibitors

por Kindler, Thomas, Cornejo, Melanie G., Scholl, Claudia, Liu, Jianing, Leeman, Dena S., Haydu, J. Erika, Fröhling, Stefan, Lee, Benjamin H., Gilliland, D. Gary
Publicado 2008

Notch Signaling Specifies Megakaryocyte Development from Hematopoietic Stem Cells

por Mercher, Thomas, Cornejo, Melanie G., Sears, Christopher, Kindler, Thomas, Moore, Sandra A., Maillard, Ivan, Pear, Warren S., Aster, Jon C., Gilliland, D. Gary
Publicado 2008

Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells

por Lipka, Daniel B., Wagner, Marie-Christine, Dziadosz, Marek, Schnöder, Tina, Heidel, Florian, Schemionek, Mirle, Melo, Junia V., Kindler, Thomas, Müller-Tidow, Carsten, Koschmieder, Steffen, Fischer, Thomas
Publicado 2012

Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors

por Knauer, Shirley K., Fetz, Verena, Rabenstein, Jens, Friedl, Sandra, Hofmann, Bettina, Sabiani, Samaneh, Schröder, Elisabeth, Kunst, Lena, Proschak, Eugen, Thines, Eckhard, Kindler, Thomas, Schneider, Gisbert, Marschalek, Rolf, Stauber, Roland H., Bier, Carolin
Publicado 2011

CD19 Isoforms Enabling Resistance to CART-19 Immunotherapy Are Expressed in B-ALL Patients at Initial Diagnosis

por Fischer, Jeannette, Paret, Claudia, El Malki, Khalifa, Alt, Francesca, Wingerter, Arthur, Neu, Marie A., Kron, Bettina, Russo, Alexandra, Lehmann, Nadine, Roth, Lea, Fehr, Eva-M., Attig, Sebastian, Hohberger, Alexander, Kindler, Thomas, Faber, Jörg
Publicado en J Immunother (2017)

Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis

por Spiecker, Lisa, Witte, Ines, Mehlig, Julia, Shah, Viral, Meyerhöfer, Markus, Haehnel, Patricia S., Petermann, Victoria, Schüler, Andrea, More, Piyush, Cabezas-Wallscheid, Nina, Horke, Sven, Pautz, Andrea, Daiber, Andreas, Sasca, Daniel, Kindler, Thomas, Kleinert, Hartmut
Publicado en Oxid Med Cell Longev (2021)

STAT5 Is Crucial to Maintain Leukemic Stem Cells in Acute Myelogenous Leukemias Induced by MOZ-TIF2

por Tam, Winnie F., Hähnel, Patricia S., Schüler, Andrea, Lee, Benjamin H., Okabe, Rachel, Zhu, Nan, Pante, Saskia V., Raffel, Glen, Mercher, Thomas, Wernig, Gerlinde, Bockamp, Ernesto, Sasca, Daniel, Kreft, Andreas, Robinson, Gertraud W., Hennighausen, Lothar, Gilliland, D. Gary, Kindler, Thomas
Publicado 2012

Exploiting Gangliosides for the Therapy of Ewing’s Sarcoma and H3K27M-Mutant Diffuse Midline Glioma

por Wingerter, Arthur, El Malki, Khalifa, Sandhoff, Roger, Seidmann, Larissa, Wagner, Daniel-Christoph, Lehmann, Nadine, Vewinger, Nadine, Frauenknecht, Katrin B. M., Sommer, Clemens J., Traub, Frank, Kindler, Thomas, Russo, Alexandra, Otto, Henrike, Lollert, André, Staatz, Gundula, Roth, Lea, Paret, Claudia, Faber, Jörg
Publicado en Cancers (Basel) (2021)

Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition

por Dzama, Margarita M., Steiner, Marlene, Rausch, Johanna, Sasca, Daniel, Schönfeld, Jonas, Kunz, Kerstin, Taubert, Martha C., McGeehan, Gerard M., Chen, Chun-Wei, Mupo, Annalisa, Hähnel, Patricia, Theobald, Matthias, Kindler, Thomas, Koche, Richard P., Vassiliou, George S., Armstrong, Scott A., Kühn, Michael W. M.
Publicado en Blood (2020)

Safety and Activity of the Combination of Ceritinib and Dasatinib in Osteosarcoma

por Beck, Olaf, Paret, Claudia, Russo, Alexandra, Burhenne, Jürgen, Fresnais, Margaux, Steimel, Kevin, Seidmann, Larissa, Wagner, Daniel-Christoph, Vewinger, Nadine, Lehmann, Nadine, Sprang, Maximilian, Backes, Nora, Roth, Lea, Neu, Marie Astrid, Wingerter, Arthur, Henninger, Nicole, El Malki, Khalifa, Otto, Henrike, Alt, Francesca, Desuki, Alexander, Kindler, Thomas, Faber, Joerg
Publicado en Cancers (Basel) (2020)

ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group

por Paschka, Peter, Schlenk, Richard F., Gaidzik, Verena I., Herzig, Julia K., Aulitzky, Teresa, Bullinger, Lars, Späth, Daniela, Teleanu, Veronika, Kündgen, Andrea, Köhne, Claus-Henning, Brossart, Peter, Held, Gerhard, Horst, Heinz-A., Ringhoffer, Mark, Götze, Katharina, Nachbaur, David, Kindler, Thomas, Heuser, Michael, Thol, Felicitas, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze
Publicado en Haematologica (2015)

Requirement for YAP1 signaling in myxoid liposarcoma

por Trautmann, Marcel, Cheng, Ya‐Yun, Jensen, Patrizia, Azoitei, Ninel, Brunner, Ines, Hüllein, Jennifer, Slabicki, Mikolaj, Isfort, Ilka, Cyra, Magdalene, Berthold, Ruth, Wardelmann, Eva, Huss, Sebastian, Altvater, Bianca, Rossig, Claudia, Hafner, Susanne, Simmet, Thomas, Ståhlberg, Anders, Åman, Pierre, Zenz, Thorsten, Lange, Undine, Kindler, Thomas, Scholl, Claudia, Hartmann, Wolfgang, Fröhling, Stefan
Publicado en EMBO Mol Med (2019)

Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model

por Cabezas-Wallscheid, Nina, Eichwald, Victoria, de Graaf, Jos, Löwer, Martin, Lehr, Hans-Anton, Kreft, Andreas, Eshkind, Leonid, Hildebrandt, Andreas, Abassi, Yasmin, Heck, Rosario, Dehof, Anna Katharina, Ohngemach, Svetlana, Sprengel, Rolf, Wörtge, Simone, Schmitt, Steffen, Lotz, Johannes, Meyer, Claudius, Kindler, Thomas, Zhang, Dong-Er, Kaina, Bernd, Castle, John C, Trumpp, Andreas, Sahin, Ugur, Bockamp, Ernesto
Publicado 2013

Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML)

por Agrawal, Mridul, Schwarz, Peggy, Giaimo, Benedetto Daniele, Bedzhov, Ivan, Corbacioglu, Andrea, Weber, Daniela, Gaidzik, Verena I., Jahn, Nikolaus, Rücker, Frank G., Schroeder, Thomas, Kindler, Thomas, Wattad, Mohammed, Götze, Katharina, Lübbert, Michael, Salwender, Hans, Ringhoffer, Mark, Lange, Elisabeth, Koller, Elisabeth, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Bullinger, Lars, Paschka, Peter, Döhner, Hartmut, Geiger, Hartmut, Borggrefe, Tilman, Döhner, Konstanze, Oswald, Franz
Publicado en Leukemia (2019)

Gemtuzumab Ozogamicin in NPM1-Mutated Acute Myeloid Leukemia: Early Results From the Prospective Randomized AMLSG 09-09 Phase III Study

por Schlenk, Richard F., Paschka, Peter, Krzykalla, Julia, Weber, Daniela, Kapp-Schwoerer, Silke, Gaidzik, Verena I., Leis, Claudia, Fiedler, Walter, Kindler, Thomas, Schroeder, Thomas, Mayer, Karin, Lübbert, Michael, Wattad, Mohammed, Götze, Katharina, Horst, Heinz A., Koller, Elisabeth, Wulf, Gerald, Schleicher, Jan, Bentz, Martin, Greil, Richard, Hertenstein, Bernd, Krauter, Jürgen, Martens, Uwe, Nachbaur, David, Abu Samra, Maisun, Girschikofsky, Michael, Basara, Nadezda, Benner, Axel, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Konstanze, Döhner, Hartmut
Publicado en J Clin Oncol (2020)

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

por Hartwell, Kimberly A, Miller, Peter G, Mukherjee, Siddhartha, Kahn, Alissa R, Stewart, Alison L, Logan, David J, Negri, Joseph M, Duvet, Mildred, Järås, Marcus, Puram, Rishi, Dancik, Vlado, Al-Shahrour, Fatima, Kindler, Thomas, Tothova, Zuzana, Chattopadhyay, Shrikanta, Hasaka, Thomas, Narayan, Rajiv, Dai, Mingji, Huang, Christina, Shterental, Sebastian, Chu, Lisa P, Haydu, J Erika, Shieh, Jae Hung, Steensma, David P, Munoz, Benito, Bittker, Joshua A, Shamji, Alykhan F, Clemons, Paul A, Tolliday, Nicola J, Carpenter, Anne E, Gilliland, D Gary, Stern, Andrew M, Moore, Malcolm A S, Scadden, David T, Schreiber, Stuart L, Ebert, Benjamin L, Golub, Todd R
Publicado 2013