Requirement for YAP1 signaling in myxoid liposarcoma

Myxoid liposarcomas (MLS), malignant tumors of adipocyte origin, are driven by the FUS‐DDIT3 fusion gene encoding an aberrant transcription factor. The mechanisms whereby FUS‐DDIT3 mediates sarcomagenesis are incompletely understood, and strategies to selectively target MLS cells remain elusive. Her...

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Publicat a:EMBO Mol Med
Autors principals: Trautmann, Marcel, Cheng, Ya‐Yun, Jensen, Patrizia, Azoitei, Ninel, Brunner, Ines, Hüllein, Jennifer, Slabicki, Mikolaj, Isfort, Ilka, Cyra, Magdalene, Berthold, Ruth, Wardelmann, Eva, Huss, Sebastian, Altvater, Bianca, Rossig, Claudia, Hafner, Susanne, Simmet, Thomas, Ståhlberg, Anders, Åman, Pierre, Zenz, Thorsten, Lange, Undine, Kindler, Thomas, Scholl, Claudia, Hartmann, Wolfgang, Fröhling, Stefan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505681/
https://ncbi.nlm.nih.gov/pubmed/30898787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809889
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