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Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells

Recently approved cancer drugs remain out-of-reach to most patients due to prohibitive costs and only few produce clinically meaningful benefits. An untapped alternative is to enhance the efficacy and safety of existing cancer drugs. We hypothesized that the response to topoisomerase II poisons, a v...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: More, Piyush, Goedtel-Armbrust, Ute, Shah, Viral, Mathaes, Marianne, Kindler, Thomas, Andrade-Navarro, Miguel A., Wojnowski, Leszek
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731103/
https://ncbi.nlm.nih.gov/pubmed/31523390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27112
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