Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors

BACKGROUND: Threonine Aspartase 1 (Taspase1) mediates cleavage of the mixed lineage leukemia (MLL) protein and leukemia provoking MLL-fusions. In contrast to other proteases, the understanding of Taspase1's (patho)biological relevance and function is limited, since neither small molecule inhibi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Knauer, Shirley K., Fetz, Verena, Rabenstein, Jens, Friedl, Sandra, Hofmann, Bettina, Sabiani, Samaneh, Schröder, Elisabeth, Kunst, Lena, Proschak, Eugen, Thines, Eckhard, Kindler, Thomas, Schneider, Gisbert, Marschalek, Rolf, Stauber, Roland H., Bier, Carolin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102056/
https://ncbi.nlm.nih.gov/pubmed/21647428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018253
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados