Genomic Classification and Prognosis in Acute Myeloid Leukemia

BACKGROUND: Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice. METHODS: We enrolled a total of 1540 patients in thre...

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發表在:N Engl J Med
Main Authors: Papaemmanuil, Elli, Gerstung, Moritz, Bullinger, Lars, Gaidzik, Verena I., Paschka, Peter, Roberts, Nicola D., Potter, Nicola E., Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Gundem, Gunes, Van Loo, Peter, Martincorena, Inigo, Ganly, Peter, Mudie, Laura, McLaren, Stuart, O’Meara, Sarah, Raine, Keiran, Jones, David R., Teague, Jon W., Butler, Adam P., Greaves, Mel F., Ganser, Arnold, Döhner, Konstanze, Schlenk, Richard F., Döhner, Hartmut, Campbell, Peter J.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979995/
https://ncbi.nlm.nih.gov/pubmed/27276561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1516192
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