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Genomic Classification and Prognosis in Acute Myeloid Leukemia

BACKGROUND: Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice. METHODS: We enrolled a total of 1540 patients in thre...

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Bibliographic Details
Published in:N Engl J Med
Main Authors: Papaemmanuil, Elli, Gerstung, Moritz, Bullinger, Lars, Gaidzik, Verena I., Paschka, Peter, Roberts, Nicola D., Potter, Nicola E., Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Gundem, Gunes, Van Loo, Peter, Martincorena, Inigo, Ganly, Peter, Mudie, Laura, McLaren, Stuart, O’Meara, Sarah, Raine, Keiran, Jones, David R., Teague, Jon W., Butler, Adam P., Greaves, Mel F., Ganser, Arnold, Döhner, Konstanze, Schlenk, Richard F., Döhner, Hartmut, Campbell, Peter J.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979995/
https://ncbi.nlm.nih.gov/pubmed/27276561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1516192
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