Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: A review

od Morgan, Meredith A., Parsels, Leslie A., Maybaum, Jonathan, Lawrence, Theodore S.
Izdano 2008

Improving the efficacy of chemoradiation with targeted agents

od Morgan, Meredith A., Parsels, Leslie A., Maybaum, Jonathan, Lawrence, Theodore S.
Izdano 2014

Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments

od Zhao, Lili, Morgan, Meredith A., Parsels, Leslie A., Maybaum, Jonathan, Lawrence, Theodore S., Normolle, Daniel
Izdano 2010

The combination of EGFR inhibitors with gemcitabine and radiation in pancreatic cancer

od Morgan, Meredith A., Parsels, Leslie A., Kollar, Laura E., Normolle, Daniel P., Maybaum, Jonathan, Lawrence, Theodore S.
Izdano 2008

The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors

od Parsels, Leslie A., Parsels, Joshua D., Tanska, Daria M., Maybaum, Jonathan, Lawrence, Theodore S., Morgan, Meredith A.
izdano v Cell Cycle (2018)

Characterization of a cis-acting regulatory element in the protein coding region of thymidylate synthase mRNA

od Lin, Xiukun, Parsels, Leslie A., Voeller, Donna M., Allegra, Carmen J., Maley, Gladys F., Maley, Frank, Chu, Edward
Izdano 2000

Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry

od Parsels, Leslie A., Tanska, Daria M., Parsels, Joshua D., Zabludoff, Sonya D., Cuneo, Kyle C., Lawrence, Theodore S., Maybaum, Jonathan, Morgan, Meredith A.
izdano v Cell Cycle (2016)

Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1

od Vance, Sean M, Liu, Erqi, Zhao, Lili, Parsels, Joshua D, Parsels, Leslie A, Brown, Jeffrey L, Maybaum, Jonathan, Lawrence, Theodore S, Morgan, Meredith A
Izdano 2011

Sensitization of Pancreatic Cancer Stem Cells to Gemcitabine by Chk1 Inhibition

od Venkatesha, Venkatasubbaiah A, Parsels, Leslie A, Parsels, Joshua D, Zhao, Lili, Zabludoff, Sonya D, Simeone, Diane M, Maybaum, Jonathan, Lawrence, Theodore S, Morgan, Meredith A
Izdano 2012

Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair

od Wei, Dongping, Parsels, Leslie A., Karnak, David, Davis, Mary A., Parsels, Joshua D., Zhao, Lili, Maybaum, Jonathan, Lawrence, Theodore S., Sun, Yi, Morgan, Meredith A.
Izdano 2013

Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers()()

od Wei, Dongping, Zhang, Qiang, Schreiber, Jason S., Parsels, Leslie A., Abulwerdi, Fardokht A., Kausar, Tasneem, Lawrence, Theodore S., Sun, Yi, Nikolovska-Coleska, Zaneta, Morgan, Meredith A.
izdano v Transl Oncol (2015)

Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair()()

od Kausar, Tasneem, Schreiber, Jason S., Karnak, David, Parsels, Leslie A., Parsels, Joshua D., Davis, Mary A., Zhao, Lili, Maybaum, Jonathan, Lawrence, Theodore S., Morgan, Meredith A.
izdano v Neoplasia (2015)

Combinatorial efficacy of olaparib with radiation and ATR inhibitor requires PARP1 protein in homologous recombination proficient pancreatic cancer

od Parsels, Leslie A., Engelke, Carl G., Parsels, Joshua, Flanagan, Sheryl A., Zhang, Qiang, Tanska, Daria, Wahl, Daniel R., Canman, Christine E., Lawrence, Theodore S., Morgan, Meredith A.
izdano v Mol Cancer Ther (2020)

Combined inhibition of Wee1 and PARP1/2 for radiosensitization in pancreatic cancer

od Karnak, David, Engelke, Carl G., Parsels, Leslie A., Kausar, Tasneem, Wei, Dongping, Robertson, Jordan R., Marsh, Katherine B., Davis, Mary A., Zhao, Lili, Maybaum, Jonathan, Lawrence, Theodore S., Morgan, Meredith A.
Izdano 2014

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors

od Parsels, Leslie A., Karnak, David, Parsels, Joshua D., Zhang, Qiang, Vélez-Padilla, Jonathan, Reichert, Zachery R., Wahl, Daniel R., Maybaum, Jonathan, O’Connor, Mark J., Lawrence, Theodore S., Morgan, Meredith A.
izdano v Mol Cancer Res (2017)

Gemcitabine sensitization by Chk1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

od Parsels, Leslie A., Morgan, Meredith A., Tanska, Daria M., Parsels, Joshua D., Palmer, Brian D., Booth, R. John, Denny, William A., Canman, Christine E., Kraker, Alan J., Lawrence, Theodore S., Maybaum, Jonathan
Izdano 2009

Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer

od Cuneo, Kyle C., Morgan, Meredith A., Sahai, Vaibhav, Schipper, Matthew J., Parsels, Leslie A., Parsels, Joshua D., Devasia, Theresa, Al-Hawaray, Mahmoud, Cho, Clifford S., Nathan, Hari, Maybaum, Jonathan, Zalupski, Mark M., Lawrence, Theodore S.
izdano v J Clin Oncol (2019)

Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor, MK8776

od Engelke, Carl G., Parsels, Leslie A., Qian, Yushen, Zhang, Qiang, Karnak, David, Robertson, Jordan R., Tanska, Daria M., Wei, Dongping, Davis, Mary A., Parsels, Joshua D., Zhao, Lili, Greenson, Joel K, Lawrence, Theodore S., Maybaum, Jonathan, Morgan, Meredith A.
Izdano 2013

Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair

od Morgan, Meredith A., Parsels, Leslie A., Zha, Lili, Parsels, Joshua D., Davis, Mary A., Hassan, Maria C., Arumugarajah, Sankari, Hylander-Gans, Linda, Morosini, Deborah, Simeone, Diane M., Canman, Christine E., Normolle, Daniel P., Zabludoff, Sonya D., Maybaum, Jonathan, Lawrence, Theodore S.
Izdano 2010

Assessment of Chk1 phosphorylation as a pharmacodynamic biomarker of Chk1 inhibition

od Parsels, Leslie A., Qian, Yushen, Tanska, Daria M., Gross, Marisa, Zhao, Lili, Hassan, Maria C., Arumugarajah, Sankari, Parsels, Joshua D., Hylander-Gans, Linda, Simeone, Diane M., Morosini, Deborah, Brown, Jeffrey L., Zabludoff, Sonya D., Maybaum, Jonathan, Lawrence, Theodore S., Morgan, Meredith A.
Izdano 2011