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Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments

PURPOSE: The standard approach of using tumor doubling time to assess growth delay may not accurately represent tumor response, especially if the growth rates are not constant. Therefore, we developed a method to compare the antitumor activities of different treatments in xenograft experiments that...

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Detalhes bibliográficos
Main Authors: Zhao, Lili, Morgan, Meredith A., Parsels, Leslie A., Maybaum, Jonathan, Lawrence, Theodore S., Normolle, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048927/
https://ncbi.nlm.nih.gov/pubmed/21131555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1935
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