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Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers()()

In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes. We identified Mcl-1 (myeloid cell leukemia-1), an anti-apoptotic member of the Bcl-2 family, as a target for sensitizing pancr...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Wei, Dongping, Zhang, Qiang, Schreiber, Jason S., Parsels, Leslie A., Abulwerdi, Fardokht A., Kausar, Tasneem, Lawrence, Theodore S., Sun, Yi, Nikolovska-Coleska, Zaneta, Morgan, Meredith A.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350640/
https://ncbi.nlm.nih.gov/pubmed/25749177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2014.12.004
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