Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers()()

In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes. We identified Mcl-1 (myeloid cell leukemia-1), an anti-apoptotic member of the Bcl-2 family, as a target for sensitizing pancr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transl Oncol
Prif Awduron: Wei, Dongping, Zhang, Qiang, Schreiber, Jason S., Parsels, Leslie A., Abulwerdi, Fardokht A., Kausar, Tasneem, Lawrence, Theodore S., Sun, Yi, Nikolovska-Coleska, Zaneta, Morgan, Meredith A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350640/
https://ncbi.nlm.nih.gov/pubmed/25749177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2014.12.004
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