Proteasome Inhibitors: An Expanding Army Attacking a Unique Target

Por Kisselev, Alexei F., van der Linden, Wouter A., Overkleeft, Herman S.
Publicado em 2012

Plant Glycosides and Glycosidases: A Treasure-Trove for Therapeutics

Por Kytidou, Kassiani, Artola, Marta, Overkleeft, Herman S., Aerts, Johannes M. F. G.
Publicado no Front Plant Sci (2020)

A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i

Por Huber, Eva M, Heinemeyer, Wolfgang, de Bruin, Gerjan, Overkleeft, Herman S, Groll, Michael
Publicado no EMBO J (2016)

Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome

Por Basler, Michael, Maurits, Elmer, de Bruin, Gerjan, Koerner, Julia, Overkleeft, Herman S, Groettrup, Marcus
Publicado no Br J Pharmacol (2017)

Reagent Controlled Stereoselective Synthesis of α-Glucans

Por Wang, Liming, Overkleeft, Herman S., van der Marel, Gijsbert A., Codée, Jeroen D. C.
Publicado no J Am Chem Soc (2018)

Reagent Controlled Stereoselective Assembly of α‐(1,3)‐Glucans

Por Wang, Liming, Overkleeft, Herman S., van der Marel, Gijsbert A., Codée, Jeroen D. C.
Publicado no European J Org Chem (2018)

Structure‐Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits

Por Maurits, Elmer, Degeling, Christian G., Kisselev, Alexei F., Florea, Bogdan I., Overkleeft, Herman S.
Publicado no Chembiochem (2020)

Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses

Por Ben Bdira, Fredj, Artola, Marta, Overkleeft, Herman S., Ubbink, Marcellus, Aerts, Johannes M. F. G.
Publicado no J Lipid Res (2018)

Scope and Limitations of Boron Fluorescent Complexes from Stable Nitrile Oxides in ABPP Assays

Por Moiola, Mattia, Crespi, Stefano, Memeo, Misal, Collina, Simona, Overkleeft, Herman, Florea, Bogdan, Quadrelli, Paolo
Publicado no ACS Omega (2019)

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

Por Borodovsky, Anna, Kessler, Benedikt M., Casagrande, Rocco, Overkleeft, Herman S., Wilkinson, Keith D., Ploegh, Hidde L.
Publicado em 2001

Mapping the Reactivity and Selectivity of 2-Azidofucosyl Donors for the Assembly of N-Acetylfucosamine-Containing Bacterial Oligosaccharides

Por Hagen, Bas, Ali, Sara, Overkleeft, Herman S., van der Marel, Gijsbert A., Codée, Jeroen D. C.
Publicado no J Org Chem (2017)

Stereoselectivity of Conformationally Restricted Glucosazide Donors

Por van der Vorm, Stefan, Overkleeft, Herman S., van der Marel, Gijsbert A., Codée, Jeroen D. C.
Publicado no J Org Chem (2017)

Reagent Controlled Glycosylations for the Assembly of Well-Defined Pel Oligosaccharides

Por Wang, Liming, Zhang, Yongzhen, Overkleeft, Herman S., van der Marel, Gijsbert A., Codée, Jeroen D. C.
Publicado no J Org Chem (2020)

Detection of bioorthogonal groups by correlative light and electron microscopy allows imaging of degraded bacteria in phagocytes

Por van Elsland, Daphne M., Bos, Erik, de Boer, Wouter, Overkleeft, Herman S., Koster, Abraham J., van Kasteren, Sander I.
Publicado no Chem Sci (2016)

Synthetic α- and β-Ser-ADP-ribosylated Peptides Reveal α-Ser-ADPr as the Native Epimer

Por Voorneveld, Jim, Rack, Johannes G. M., Ahel, Ivan, Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V.
Publicado no Org Lett (2018)

Fluorescent Probes from Aromatic Polycyclic Nitrile Oxides: Isoxazoles versus Dihydro‐1λ(3),3,2λ(4)‐Oxazaborinines

Por Moiola, Mattia, Bova, Antonio, Crespi, Stefano, Memeo, Misal G., Mella, Mariella, Overkleeft, Herman S., Florea, Bogdan I., Quadrelli, Paolo
Publicado no ChemistryOpen (2019)

Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist

Por Bonger, Kimberly M., Hoogendoorn, Sascha, van Koppen, Chris J., Timmers, C. Marco, van der Marel, Gijsbert A., Overkleeft, Herman S.
Publicado em 2010

Cyanopivaloyl Ester in the Automated Solid-Phase Synthesis of Oligorhamnans

Por Geert Volbeda, Anne, van Mechelen, Jeanine, Meeuwenoord, Nico, Overkleeft, Herman S., van der Marel, Gijsbert A., Codée, Jeroen D. C.
Publicado no J Org Chem (2017)

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

Por Altun, Mikael, Besche, Henrike C., Overkleeft, Herman S., Piccirillo, Rosanna, Edelmann, Mariola J., Kessler, Benedikt M., Goldberg, Alfred L., Ulfhake, Brun
Publicado em 2010

Biochemical response to substrate reduction therapy versus enzyme replacement therapy in Gaucher disease type 1 patients

Por Smid, Bouwien E., Ferraz, Maria J., Verhoek, Marri, Mirzaian, Mina, Wisse, Patrick, Overkleeft, Herman S., Hollak, Carla E., Aerts, Johannes M.
Publicado no Orphanet J Rare Dis (2016)