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Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses
Glycosyl hydrolases (GHs) are carbohydrate-active enzymes that hydrolyze a specific β-glycosidic bond in glycoconjugate substrates; β-glucosidases degrade glucosylceramide, a ubiquitous glycosphingolipid. GHs are grouped into structurally similar families that themselves can be grouped into clans. G...
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Publicado no: | J Lipid Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277158/ https://ncbi.nlm.nih.gov/pubmed/30279220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R086629 |
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