Immunoproteasome Inhibition Impairs T and B Cell Activation by Restraining ERK Signaling and Proteostasis

par Schmidt, Christian, Berger, Thilo, Groettrup, Marcus, Basler, Michael
Publié dans Front Immunol (2018)

A Cytomegalovirus Inhibitor of Gamma Interferon Signaling Controls Immunoproteasome Induction

par Khan, Selina, Zimmermann, Albert, Basler, Michael, Groettrup, Marcus, Hengel, Hartmut
Publié 2004

Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice

par Mundt, Sarah, Basler, Michael, Buerger, Stefanie, Engler, Harald, Groettrup, Marcus
Publié dans Sci Rep (2016)

Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome

par Basler, Michael, Maurits, Elmer, de Bruin, Gerjan, Koerner, Julia, Overkleeft, Herman S, Groettrup, Marcus
Publié dans Br J Pharmacol (2017)

Immuno- and Constitutive Proteasomes Do Not Differ in Their Abilities to Degrade Ubiquitinated Proteins

par Nathan, James A., Spinnenhirn, Valentina, Schmidtke, Gunter, Basler, Michael, Groettrup, Marcus, Goldberg, Alfred L.
Publié 2013

Competitive Metabolite Profiling of Natural Products Reveals Subunit Specific Inhibitors of the 20S Proteasome

par Pawar, Atul, Basler, Michael, Goebel, Heike, Alvarez Salinas, Gerardo Omar, Groettrup, Marcus, Böttcher, Thomas
Publié dans ACS Cent Sci (2020)

Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis

par Basler, Michael, Mundt, Sarah, Muchamuel, Tony, Moll, Carlo, Jiang, Jing, Groettrup, Marcus, Kirk, Christopher J
Publié 2014

Co‐inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity

par Basler, Michael, Lindstrom, Michelle M, LaStant, Jacob J, Bradshaw, J Michael, Owens, Timothy D, Schmidt, Christian, Maurits, Elmer, Tsu, Christopher, Overkleeft, Herman S, Kirk, Christopher J, Langrish, Claire L, Groettrup, Marcus
Publié dans EMBO Rep (2018)

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency

par Treise, Irina, Huber, Eva M., Klein-Rodewald, Tanja, Heinemeyer, Wolfgang, Grassmann, Simon A., Basler, Michael, Adler, Thure, Rathkolb, Birgit, Helming, Laura, Andres, Christian, Klaften, Matthias, Landbrecht, Christina, Wieland, Thomas, Strom, Tim M., McCoy, Kathy D., Macpherson, Andrew J., Wolf, Eckhard, Groettrup, Marcus, Ollert, Markus, Neff, Frauke, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Groll, Michael, Busch, Dirk H.
Publié dans Sci Rep (2018)