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Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is a chronic demyelinating immune mediated disease of the central nervous system. The immunoproteasome is a distinct class of proteasomes found predominantly in monocytes and lymphocytes. Recently, we demonstrated a novel function of immunoproteasomes in cytokine production a...

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Autors principals: Basler, Michael, Mundt, Sarah, Muchamuel, Tony, Moll, Carlo, Jiang, Jing, Groettrup, Marcus, Kirk, Christopher J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927957/
https://ncbi.nlm.nih.gov/pubmed/24399752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201303543
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