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Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis

BACKGROUND: The secretory leukocyte protease inhibitor (SLPI) exerts wide ranging effects on inflammatory pathways and is upregulated in EAE but the biological role of SLPI in EAE, an animal model of multiple sclerosis is unknown METHODS: To investigate the pathophysiological effects of SLPI within...

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Detalhes bibliográficos
Main Authors: Müller, André Michael, Jun, Esther, Conlon, Hana, Sadiq, Saud Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352067/
https://ncbi.nlm.nih.gov/pubmed/22436018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-30
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