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Structure‐Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
Proteasomes are established therapeutic targets for hematological cancers and promising targets for autoimmune diseases. In the past, we have designed and synthesized mechanism‐based proteasome inhibitors that are selective for the individual catalytic activities of human constitutive proteasomes an...
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| Udgivet i: | Chembiochem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7754458/ https://ncbi.nlm.nih.gov/pubmed/32598532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000375 |
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