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Structure‐Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
Proteasomes are established therapeutic targets for hematological cancers and promising targets for autoimmune diseases. In the past, we have designed and synthesized mechanism‐based proteasome inhibitors that are selective for the individual catalytic activities of human constitutive proteasomes an...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Chembiochem |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
John Wiley and Sons Inc.
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7754458/ https://ncbi.nlm.nih.gov/pubmed/32598532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000375 |
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