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Subunit specific inhibitors of proteasomes and their potential for immunomodulation
Specialized variants of the constitutive 20S proteasome in the immune system like the immunoproteasomes and the thymoproteasome contain active site-bearing subunits which differ in their cleavage priorities and substrate binding pockets. The immunoproteasome plays a crucial role in antigen processin...
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| Publicat a: | Curr Opin Chem Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564373/ https://ncbi.nlm.nih.gov/pubmed/25217863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.08.012 |
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