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A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

A C-terminally modified ubiquitin (Ub) derivative, ubiquitin vinyl sulfone (UbVS), was synthesized as an active site-directed probe that irreversibly modifies a subset of Ub C-terminal hydrolases (UCHs) and Ub-specific processing proteases (UBPs). Specificity of UbVS for deubiquitylating enzymes (DU...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Borodovsky, Anna, Kessler, Benedikt M., Casagrande, Rocco, Overkleeft, Herman S., Wilkinson, Keith D., Ploegh, Hidde L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC125629/
https://ncbi.nlm.nih.gov/pubmed/11566882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.18.5187
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