HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities

von Koeneke, Emily, Witt, Olaf, Oehme, Ina
Veröffentlicht in Cells (2015)

The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

von Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef
Veröffentlicht in Redox Biol (2018)

Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer

von Dovzhanskiy, Dmitriy I, Arnold, Stefanie M, Hackert, Thilo, Oehme, Ina, Witt, Olaf, Felix, Klaus, Giese, Nathalia, Werner, Jens
Veröffentlicht 2012

MBRS-19. SYNERGISM OF HDAC AND PARP INHIBITORS IN MYC-DRIVEN GROUP 3 MEDULLOBLASTOMA CELLS

von Vollmer, Johanna, Ecker, Jonas, Hielscher, Thomas, Valinciute, Gintvile, Oppermann, Sina, Peterziel, Heike, Oehme, Ina, Witt, Olaf, Milde, Till
Veröffentlicht in Neuro Oncol (2020)

The PEA-15 Protein Regulates Autophagy via Activation of JNK

von Böck, Barbara C., Tagscherer, Katrin E., Fassl, Anne, Krämer, Anika, Oehme, Ina, Zentgraf, Hans-Walter, Keith, Martina, Roth, Wilfried
Veröffentlicht 2010

Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma

von Körholz, Katharina, Ridinger, Johannes, Krunic, Damir, Najafi, Sara, Gerloff, Xenia F., Frese, Karen, Meder, Benjamin, Peterziel, Heike, Vega-Rubin-de-Celis, Silvia, Witt, Olaf, Oehme, Ina
Veröffentlicht in Cells (2021)

MB-57 INTERACTION OF HDAC2 AND MYC IN GROUP 3 MEDULLOBLASTOMA - A NOVEL THERAPEUTIC TARGET

von Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Schnölzer, Martina, Warnken, Uwe, Brabetz, Sebastian, Wechsler-Reya, Robert, Kulozik, Andreas E., Pfister, Stefan M., Witt, Olaf, Milde, Till
Veröffentlicht in Neuro Oncol (2016)

Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts

von Wrobel, Jagoda K, Najafi, Sara, Ayhan, Simay, Gatzweiler, Charlotte, Krunic, Damir, Ridinger, Johannes, Milde, Till, Westermann, Frank, Peterziel, Heike, Meder, Benjamin, Distel, Martin, Witt, Olaf, Oehme, Ina
Veröffentlicht in Pharmaceuticals (Basel) (2020)

The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines

von Kolbinger, Fiona R., Koeneke, Emily, Ridinger, Johannes, Heimburg, Tino, Müller, Michael, Bayer, Theresa, Sippl, Wolfgang, Jung, Manfred, Gunkel, Nikolas, Miller, Aubry K., Westermann, Frank, Witt, Olaf, Oehme, Ina
Veröffentlicht in Arch Toxicol (2018)

Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance

von Bingel, Corinna, Koeneke, Emily, Ridinger, Johannes, Bittmann, Annika, Sill, Martin, Peterziel, Heike, Wrobel, Jagoda K, Rettig, Inga, Milde, Till, Fernekorn, Uta, Weise, Frank, Schober, Andreas, Witt, Olaf, Oehme, Ina
Veröffentlicht in Cell Death Dis (2017)

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

von Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne, Witt, Olaf, Oehme, Ina
Veröffentlicht in Sci Rep (2018)

MEDU-20. TARGETING OF MYC BY HDAC INHIBITION IN MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA

von Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Chavez, Lukas, Hohloch, Juliane, Valinciute, Gintvile, van Tilburg, Cornelis M., Schnölzer, Martina, Warnken, Uwe, Wechsler-Reya, Robert, Pfister, Stefan M., Witt, Olaf, Milde, Till
Veröffentlicht in Neuro Oncol (2017)

Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors

von Daskalakis, Michael, Brocks, David, Sheng, Yi-Hua, Islam, Md Saiful, Ressnerova, Alzbeta, Assenov, Yassen, Milde, Till, Oehme, Ina, Witt, Olaf, Goyal, Ashish, Kühn, Alexander, Hartmann, Mark, Weichenhan, Dieter, Jung, Manfred, Plass, Christoph
Veröffentlicht in Cell Cycle (2018)

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors

von Morgen, Michael, Steimbach, Raphael R., Géraldy, Magalie, Hellweg, Lars, Sehr, Peter, Ridinger, Johannes, Witt, Olaf, Oehme, Ina, Herbst‐Gervasoni, Corey J., Osko, Jeremy D., Porter, Nicholas J., Christianson, David W., Gunkel, Nikolas, Miller, Aubry K.
Veröffentlicht in ChemMedChem (2020)

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

von Ecker, Jonas, Oehme, Ina, Mazitschek, Ralph, Korshunov, Andrey, Kool, Marcel, Hielscher, Thomas, Kiss, Judit, Selt, Florian, Konrad, Carina, Lodrini, Marco, Deubzer, Hedwig E, von Deimling, Andreas, Kulozik, Andreas E, Pfister, Stefan M, Witt, Olaf, Milde, Till
Veröffentlicht in Acta Neuropathol Commun (2015)

Nestin Expression Identifies Ependymoma Patients with Poor Outcome

von Milde, Till, Hielscher, Thomas, Witt, Hendrik, Kool, Marcel, Mack, Stephen C., Deubzer, Hedwig E., Oehme, Ina, Lodrini, Marco, Benner, Axel, Taylor, Michael D., von Deimling, Andreas, Kulozik, Andreas E., Pfister, Stefan M., Witt, Olaf, Korshunov, Andrey
Veröffentlicht in Brain Pathol (2012)

MBRS-12. INTERFERENCE WITH THE FUNCTION OF MYC IN GROUP 3 MEDULLOBLASTOMA

von Ecker, Jonas, Thatikonda, Venu, Oehme, Ina, Valinciute, Gintvile, Selt, Florian, Buhl, Juliane L, Usta, Diren, van Tilburg, Cornelis M, Herold-Mende, Christel, Schnölzer, Martina, Warnken, Uwe, Kool, Marcel, Jäger, Natalie, Pfister, Stefan M, Witt, Olaf, Milde, Till
Veröffentlicht in Neuro Oncol (2018)

A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

von Shen, Jing, Najafi, Sara, Stäble, Sina, Fabian, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Wrobel, Jagoda K., Meder, Benjamin, Distel, Martin, Heimburg, Tino, Sippl, Wolfgang, Jung, Manfred, Peterziel, Heike, Kranz, Dominique, Boutros, Michael, Westermann, Frank, Witt, Olaf, Oehme, Ina
Veröffentlicht in Cell Death Differ (2018)

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

von Lodrini, Marco, Oehme, Ina, Schroeder, Christina, Milde, Till, Schier, Marie C., Kopp-Schneider, Annette, Schulte, Johannes H., Fischer, Matthias, De Preter, Katleen, Pattyn, Filip, Castoldi, Mirco, Muckenthaler, Martina U., Kulozik, Andreas E., Westermann, Frank, Witt, Olaf, Deubzer, Hedwig E.
Veröffentlicht 2013

PDTM-47. CHARACTERIZATION OF THE SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE IN PILOCYTIC ASTROCYTOMA AND ITS ROLE IN ONCOGENE-INDUCED SENESCENCE

von Hohloch, Juliane, Selt, Florian, Hielscher, Thomas, Sahm, Felix, Capper, David, Usta, Diren, Ecker, Jonas, Oehme, Ina, van Tilburg, Cornelis M, von Deimling, Andreas, Schuhmann, Martin U, Korshunov, Andrey, Jones, David, Brummer, Tilman, Pfister, Stefan M, Witt, Olaf, Milde, Till
Veröffentlicht in Neuro Oncol (2017)