Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

INTRODUCTION: Medulloblastoma (MB) is the most frequent malignant brain tumor in children. Four subgroups with distinct genetic, epigenetic and clinical characteristics have been identified. Survival remains particularly poor in patients with Group 3 tumors harbouring a MYC amplification. We herein...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Ecker, Jonas, Oehme, Ina, Mazitschek, Ralph, Korshunov, Andrey, Kool, Marcel, Hielscher, Thomas, Kiss, Judit, Selt, Florian, Konrad, Carina, Lodrini, Marco, Deubzer, Hedwig E, von Deimling, Andreas, Kulozik, Andreas E, Pfister, Stefan M, Witt, Olaf, Milde, Till
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382927/
https://ncbi.nlm.nih.gov/pubmed/25853389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0201-7
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