Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

INTRODUCTION: Medulloblastoma (MB) is the most frequent malignant brain tumor in children. Four subgroups with distinct genetic, epigenetic and clinical characteristics have been identified. Survival remains particularly poor in patients with Group 3 tumors harbouring a MYC amplification. We herein...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Ecker, Jonas, Oehme, Ina, Mazitschek, Ralph, Korshunov, Andrey, Kool, Marcel, Hielscher, Thomas, Kiss, Judit, Selt, Florian, Konrad, Carina, Lodrini, Marco, Deubzer, Hedwig E, von Deimling, Andreas, Kulozik, Andreas E, Pfister, Stefan M, Witt, Olaf, Milde, Till
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382927/
https://ncbi.nlm.nih.gov/pubmed/25853389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0201-7
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