MEDU-20. TARGETING OF MYC BY HDAC INHIBITION IN MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA

High-risk medulloblastoma (MB) remains a deadly disease with poor overall survival despite aggressive multi-modal treatment. Survivors suffer from important treatment-associated morbidity. Patients with Group 3 MB tumors with amplification or high expression of the transcription factor MYC have a pa...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Chavez, Lukas, Hohloch, Juliane, Valinciute, Gintvile, van Tilburg, Cornelis M., Schnölzer, Martina, Warnken, Uwe, Wechsler-Reya, Robert, Pfister, Stefan M., Witt, Olaf, Milde, Till
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Abstracts
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475139/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.170
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