MEDU-20. TARGETING OF MYC BY HDAC INHIBITION IN MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA

High-risk medulloblastoma (MB) remains a deadly disease with poor overall survival despite aggressive multi-modal treatment. Survivors suffer from important treatment-associated morbidity. Patients with Group 3 MB tumors with amplification or high expression of the transcription factor MYC have a pa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Chavez, Lukas, Hohloch, Juliane, Valinciute, Gintvile, van Tilburg, Cornelis M., Schnölzer, Martina, Warnken, Uwe, Wechsler-Reya, Robert, Pfister, Stefan M., Witt, Olaf, Milde, Till
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Abstracts
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475139/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.170
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