MEDU-01. HDACi AND PLK1i ACT SYNERGISTICALLY IN MYC-AMPLIFIED MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common malignant brain tumor in children. Patients with MYC-amplified Group 3 MBs exhibit particularly poor survival rates even after intensive therapy, and surviving patients often suffer from long-term sequelae. Poor survival rates and sequelae call for new therape...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Valinciute, Gintvile, Ecker, Jonas, Hielscher, Thomas, Schmidt, Christin, Remke, Marc, Sigismondo, Gianluca, Krijgsveld, Jeroen, Pfister, Stefan, Witt, Olaf, Milde, Till
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Medulloblastoma
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477443/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.161
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