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Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma

Depending on context and tumor stage, deregulation of autophagy can either suppress tumorigenesis or promote chemoresistance and tumor survival. Histone deacetylases (HDACs) can modulate autophagy; however, the exact mechanisms are not fully understood. Here, we analyze the effects of the broad-spec...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Körholz, Katharina, Ridinger, Johannes, Krunic, Damir, Najafi, Sara, Gerloff, Xenia F., Frese, Karen, Meder, Benjamin, Peterziel, Heike, Vega-Rubin-de-Celis, Silvia, Witt, Olaf, Oehme, Ina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144997/
https://ncbi.nlm.nih.gov/pubmed/33923163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051001
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