Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma

Depending on context and tumor stage, deregulation of autophagy can either suppress tumorigenesis or promote chemoresistance and tumor survival. Histone deacetylases (HDACs) can modulate autophagy; however, the exact mechanisms are not fully understood. Here, we analyze the effects of the broad-spec...

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Pubblicato in:Cells
Autori principali: Körholz, Katharina, Ridinger, Johannes, Krunic, Damir, Najafi, Sara, Gerloff, Xenia F., Frese, Karen, Meder, Benjamin, Peterziel, Heike, Vega-Rubin-de-Celis, Silvia, Witt, Olaf, Oehme, Ina
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144997/
https://ncbi.nlm.nih.gov/pubmed/33923163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051001
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