The PEA-15 Protein Regulates Autophagy via Activation of JNK

PEA-15/PED (phosphoprotein enriched in astrocytes 15 kDa/phosphoprotein enriched in diabetes) is a death effector domain-containing protein which is known to modulate apoptotic cell death. The mechanism by which PEA-15 inhibits caspase activation and increases ERK (extracellular-regulated kinase) ac...

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Autors principals: Böck, Barbara C., Tagscherer, Katrin E., Fassl, Anne, Krämer, Anika, Oehme, Ina, Zentgraf, Hans-Walter, Keith, Martina, Roth, Wilfried
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898427/
https://ncbi.nlm.nih.gov/pubmed/20452983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096628
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