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Expression and Functional Characterization of the BNIP3 Protein in Renal Cell Carcinomas

BNIP3 (Bcl-2/adenovirus E1B 19-kDa interacting protein 3) is a BH3-only protein that regulates apoptosis and autophagy. BNIP3 plays also an important role in hypoxia-induced cell response and is regulated by HIF1. Here, we studied a possible association of BNIP3 expression and the prognosis of patie...

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Библиографические подробности
Опубликовано в: :Transl Oncol
Главные авторы: Macher-Goeppinger, Stephan, Keith, Martina, Hatiboglu, Gencay, Hohenfellner, Markus, Schirmacher, Peter, Roth, Wilfried, Tagscherer, Katrin E.
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602480/
https://ncbi.nlm.nih.gov/pubmed/28918350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.08.008
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