Prognostic and Predictive Value of Tumor-infiltrating Leukocytes and of Immune Checkpoint Molecules PD1 and PDL1 in Clear Cell Renal Cell Carcinoma

INTRODUCTION: Immune checkpoint inhibitors (ICI) have been approved for patients with clear cell renal cell carcinoma (ccRCC), but not all patients benefit from ICI. One reason is the tumor microenvironment (TME) that has substantial influence on patient's prognosis and therapy response. Thus,...

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Pubblicato in:Transl Oncol
Autori principali: Stenzel, Philipp J., Schindeldecker, Mario, Tagscherer, Katrin E., Foersch, Sebastian, Herpel, Esther, Hohenfellner, Markus, Hatiboglu, Gencay, Alt, Juergen, Thomas, Christian, Haferkamp, Axel, Roth, Wilfried, Macher-Goeppinger, Stephan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2019
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031108/
https://ncbi.nlm.nih.gov/pubmed/31881506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.11.002
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