The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker

Inhibitors of the mTOR pathway, such as everolimus, are promising compounds to treat patients with renal cell carcinomas (RCCs). However, the precise mechanisms of action are far from clear, and biomarkers predicting the response to mTOR inhibitors are still missing. Here, we provide evidence that i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Knoll, Maximilian, Macher-Goeppinger, Stephan, Kopitz, Jürgen, Duensing, Stefan, Pahernik, Sascha, Hohenfellner, Markus, Schirmacher, Peter, Roth, Wilfried
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808008/
https://ncbi.nlm.nih.gov/pubmed/26506236
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