Harnessing the p53-PUMA Axis to Overcome DNA Damage Resistance in Renal Cell Carcinoma()

Resistance to DNA damage–induced apoptosis is a hallmark of cancer and a major cause of treatment failure and lethal disease outcome. A tumor entity that is largely resistant to DNA-damaging therapies including chemo- or radiotherapy is renal cell carcinoma (RCC). This study was designed to explore...

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Опубликовано в: :Neoplasia
Главные авторы: Zhou, Xiaoguang, Tolstov, Yanis, Arslan, Aysenur, Roth, Wilfried, Grüllich, Carsten, Pahernik, Sascha, Hohenfellner, Markus, Duensing, Stefan
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309250/
https://ncbi.nlm.nih.gov/pubmed/25499216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.09.012
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