PEA-15 Induces Autophagy in Human Ovarian Cancer Cells and is Associated with Prolonged Overall Survival

Phospho-enriched protein in astrocytes (PEA-15) is a 15-kDa phosphoprotein that slows cell proliferation by binding to and sequestering extracellular signal-regulated kinase (ERK) in the cytoplasm, thereby inhibiting ERK-dependent transcription and proliferation. In previous studies of E1A human gen...

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Hlavní autoři: Bartholomeusz, Chandra, Rosen, Daniel, Wei, Caimiao, Kazansky, Anna, Yamasaki, Fumiyuki, Takahashi, Takeshi, Itamochi, Hiroaki, Kondo, Seiji, Liu, Jinsong, Ueno, Naoto T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676677/
https://ncbi.nlm.nih.gov/pubmed/19010903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2592
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