MEK1/2 Inhibitor Selumetinib (AZD6244) Inhibits Growth of Ovarian Clear Cell Carcinoma in a PEA-15-dependent Manner in a Mouse Xenograft Model

Clear cell carcinoma (CCC) of the ovary tends to show resistance to standard chemotherapy, which results in poor survival for patients with CCC. Developing a novel therapeutic strategy is imperative to improve patient prognosis. Epidermal growth factor receptor (EGFR) is frequently expressed in epit...

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Bibliografiset tiedot
Päätekijät: Bartholomeusz, Chandra, Oishi, Tetsuro, Saso, Hitomi, Akar, Ugur, Liu, Ping, Kondo, Kimie, Kazansky, Anna, Krishnamurthy, Savitri, Lee, Jangsoon, Esteva, Francisco J., Kigawa, Junzo, Ueno, Naoto T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320047/
https://ncbi.nlm.nih.gov/pubmed/22144664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0400
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