A class I histone deacetylase inhibitor, entinostat, enhances lapatinib efficacy in HER2-overexpressing breast cancer cells through FOXO3-mediated Bim1 expression

Por Lee, Jangsoon, Bartholomeusz, Chandra, Mansour, Oula, Humphries, Juliane, Hortobagyi, Gabriel N., Ordentlich, Peter, Ueno, Naoto T.
Publicado em 2014

Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis

Por Su, Fei, Wang, Xiaoping, Pearson, Troy, Lee, Jangsoon, Krishnamurthy, Savitri, Ueno, Naoto T., Kolonin, Mikhail G.
Publicado no Mol Ther Oncolytics (2020)

Histone deacetylase inhibitor enhances the efficacy of MEK inhibitor through NOXA-mediated MCL1 degradation in triple-negative and inflammatory breast cancer

Por Torres-Adorno, Angie M., Lee, Jangsoon, Kogawa, Takahiro, Ordentlich, Peter, Tripathy, Debu, Lim, Bora, Ueno, Naoto T.
Publicado no Clin Cancer Res (2017)

cMET Activation and EGFR-Directed Therapy Resistance in Triple-Negative Breast Cancer

Por Sohn, Joohyuk, Liu, Shuying, Parinyanitikul, Napa, Lee, Jangsoon, Hortobagyi, Gabriel N., Mills, Gordon B., Ueno, Naoto T., Gonzalez-Angulo, Ana M.
Publicado em 2014

Comprehensive Two- and Three-Dimensional RNAi Screening Identifies PI3K Inhibition as a Complement to MEK Inhibitor AS703026 for Combination Treatment of Triple-Negative Breast Can...

Por Lee, Jangsoon, Galloway, Rachael, Grandjean, Geoff, Jacob, Justin, Humphries, Juliane, Bartholomeusz, Chandra, Goodstal, Samantha, Lim, Bora, Bartholomeusz, Geoffrey, Ueno, Naoto T., Rao, Arvind
Publicado no J Cancer (2015)

Anti-tumor and anti-metastasis efficacy of E6201, a MEK1 inhibitor, in preclinical models of triple-negative breast cancer

Por Lee, Jangsoon, Lim, Bora, Pearson, Troy, Choi, Kuicheon, Fuson, Jon A., Bartholomeusz, Chandra, Paradiso, Linda J., Myers, Thomas, Tripathy, Debu, Ueno, Naoto T.
Publicado no Breast Cancer Res Treat (2019)

MEK inhibitor selumetinib (AZD6244; ARRY-142886) prevents lung metastasis in a triple-negative breast cancer xenograft model

Por Bartholomeusz, Chandra, Xie, Xuemei, Pitner, Mary Kathryn, Kondo, Kimie, Dadbin, Ali, Lee, Jangsoon, Saso, Hitomi, Smith, Paul D., Dalby, Kevin N., Ueno, Naoto T.
Publicado no Mol Cancer Ther (2015)

Prevention of Bronchial Hyperplasia by EGFR Pathway Inhibitors in an Organotypic Culture Model

Por Lee, Jangsoon, Ryu, Seung-Hee, Kang, Shin Myung, Chung, Wen-Cheng, Gold, Kathryn Ann, Kim, Edward S., Hittelman, Walter N., Hong, Waun Ki, Koo, Ja Seok
Publicado em 2011

MEK1/2 Inhibitor Selumetinib (AZD6244) Inhibits Growth of Ovarian Clear Cell Carcinoma in a PEA-15-dependent Manner in a Mouse Xenograft Model

Por Bartholomeusz, Chandra, Oishi, Tetsuro, Saso, Hitomi, Akar, Ugur, Liu, Ping, Kondo, Kimie, Kazansky, Anna, Krishnamurthy, Savitri, Lee, Jangsoon, Esteva, Francisco J., Kigawa, Junzo, Ueno, Naoto T.
Publicado em 2011

Development of PEA-15 using a potent non-viral vector for therapeutic application in breast cancer

Por Xie, Xinhua, Tang, Hailin, Pengliu, Kong, Yanan, Wu, Minqing, Xiao, Xiangsheng, Yang, Lu, Gao, Jie, Wei, Weidong, Lee, Jangsoon, Bartholomeusz, Chandra, Ueno, Naoto T., Xie, Xiaoming
Publicado no Cancer Lett (2014)

Identification of triple-negative breast cancer cell lines classified under the same molecular subtype using different molecular characterization techniques: Implications for trans...

Por Espinosa Fernandez, Jose Rodrigo, Eckhardt, Bedrich L., Lee, Jangsoon, Lim, Bora, Pearson, Troy, Seitz, Rob S., Hout, David R., Schweitzer, Brock L., Nielsen, Tyler J., Lawrence, O. Rayne, Wang, Ying, Rao, Arvind, Ueno, Naoto T.
Publicado no PLoS One (2020)

A phase Ib study of entinostat plus lapatinib with or without trastuzumab in patients with HER2-positive metastatic breast cancer that progressed during trastuzumab treatment

Por Lim, Bora, Murthy, Rashmi K., Lee, Jangsoon, Jackson, Summer A., Iwase, Toshiaki, Davis, Darren W., Willey, Jie S., Wu, Jimin, Shen, Yu, Tripathy, Debu, Alvarez, Ricardo, Ibrahim, Nuhad K., Brewster, Abenaa M., Barcenas, Carlos H., Brown, Powel H., Giordano, Sharon H., Moulder, Stacy L., Booser, Daniel J., Moscow, Jeffrey A., Piekarz, Richard, Valero, Vicente, Ueno, Naoto T.
Publicado no Br J Cancer (2019)