cMET Activation and EGFR-Directed Therapy Resistance in Triple-Negative Breast Cancer

Background: EGFR expression and pathway activation are common in triple-negative breast cancer (TNBC). However, anti-EGFR therapies have not been effective in these patients. We aimed to study the efficacy of targeting MET in overcoming resistance to EGFR therapy in TNBC cell lines. Methods: TNBC li...

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Главные авторы: Sohn, Joohyuk, Liu, Shuying, Parinyanitikul, Napa, Lee, Jangsoon, Hortobagyi, Gabriel N., Mills, Gordon B., Ueno, Naoto T., Gonzalez-Angulo, Ana M.
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2014
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216798/
https://ncbi.nlm.nih.gov/pubmed/25368674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.9696
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