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Targeting the Hepatocyte Growth Factor–cMET Axis in Cancer Therapy
The hepatocyte growth factor (HGF) and its receptor, the transmembrane tyrosine kinase cMET, promote cell proliferation, survival, motility, and invasion as well as morphogenic changes that stimulate tissue repair and regeneration in normal cells but can be co-opted during tumor growth. MET overexpr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Clinical Oncology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434988/ https://ncbi.nlm.nih.gov/pubmed/22869872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.40.3774 |
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