Cooperative effect of oncogenic MET and PIK3CA in an HGF-dominant environment in breast cancer

There is compelling evidence that oncogenic MET and PIK3CA signaling pathways contribute to breast cancer. However, the activity of pharmacological targeting of either pathway is modest. Mechanisms of resistance to these monotherapies have not been clarified. Currently commonly used mouse models are...

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Détails bibliographiques
Publié dans:Mol Cancer Ther
Auteurs principaux: Liu, Shuying, Li, Shunqiang, Wang, Bailiang, Liu, Wenbin, Gagea, Mihai, Chen, Huiqin, Sohn, Joohyuk, Parinyanitikul, Napa, Primeau, Tina, Do, Kim-Anh, Vande Woude, George F., Mendelsohn, John, Ueno, Naoto T., Mills, Gordon B., Tripathy, Debu, Gonzalez-Angulo, Ana M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357548/
https://ncbi.nlm.nih.gov/pubmed/30518672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0710
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