Inhibition of Aurora Kinase B Is Important for Biologic Activity of the Dual Inhibitors of BCR-ABL and Aurora Kinases R763/AS703569 and PHA-739358 in BCR-ABL Transformed Cells

Por Illert, Anna L., Seitz, Anna K., Rummelt, Christoph, Kreutmair, Stefanie, Engh, Richard A., Goodstal, Samantha, Peschel, Christian, Duyster, Justus, von Bubnoff, Nikolas
Publicado no PLoS One (2014)

Comprehensive Two- and Three-Dimensional RNAi Screening Identifies PI3K Inhibition as a Complement to MEK Inhibitor AS703026 for Combination Treatment of Triple-Negative Breast Can...

Por Lee, Jangsoon, Galloway, Rachael, Grandjean, Geoff, Jacob, Justin, Humphries, Juliane, Bartholomeusz, Chandra, Goodstal, Samantha, Lim, Bora, Bartholomeusz, Geoffrey, Ueno, Naoto T., Rao, Arvind
Publicado no J Cancer (2015)

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models

Por Vena, Francesca, Jia, Ruochen, Esfandiari, Arman, Garcia-Gomez, Juan J., Rodriguez-Justo, Manuel, Ma, Jianguo, Syed, Sakeena, Crowley, Lindsey, Elenbaas, Brian, Goodstal, Samantha, Hartley, John A., Hochhauser, Daniel
Publicado no Oncotarget (2018)