Comprehensive Two- and Three-Dimensional RNAi Screening Identifies PI3K Inhibition as a Complement to MEK Inhibitor AS703026 for Combination Treatment of Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a major cause of death among breast cancer patients that results from intrinsic and acquired resistance to systemic chemotherapies. To identify novel targets for effective treatment of TNBC through combination strategies with MEK inhibitor (AS703026), we used...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Cancer
Main Authors: Lee, Jangsoon, Galloway, Rachael, Grandjean, Geoff, Jacob, Justin, Humphries, Juliane, Bartholomeusz, Chandra, Goodstal, Samantha, Lim, Bora, Bartholomeusz, Geoffrey, Ueno, Naoto T., Rao, Arvind
פורמט: Artigo
שפה:Inglês
יצא לאור: Ivyspring International Publisher 2015
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643087/
https://ncbi.nlm.nih.gov/pubmed/26640591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.13266
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