Anomalous dispersion analysis of inhibitor flexibility: a case study of the kinase inhibitor H-89

Por Pflug, Alexander, Johnson, Kenneth A., Engh, Richard A.
Publicado em 2012

Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization

Por Thakkar, Balmukund S., Svendsen, John Sigurd M., Engh, Richard A.
Publicado no Molecules (2018)

Evaluating the Predictivity of Virtual Screening for Abl Kinase Inhibitors to Hinder Drug Resistance

Por Gani, Osman A B S M, Narayanan, Dilip, Engh, Richard A
Publicado no Chem Biol Drug Des (2013)

Dynamical models of mutated chronic myelogenous leukemia cells for a post-imatinib treatment scenario: Response to dasatinib or nilotinib therapy

Por Woywod, Clemens, Gruber, Franz X., Engh, Richard A., Flå, Tor
Publicado no PLoS One (2017)

Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR

Por Narayanan, Dilip, Gani, Osman A. B. S. M., Gruber, Franz X. E., Engh, Richard A.
Publicado no J Cheminform (2017)

New enzyme lineages by subdomain shuffling

Por Hopfner, Karl-Peter, Kopetzki, Erhard, Kreße, Georg-Burkhard, Bode, Wolfram, Huber, Robert, Engh, Richard A.
Publicado em 1998

Differential Sensitivity of ERBB2 Kinase Domain Mutations towards Lapatinib

Por Kancha, Rama Krishna, von Bubnoff, Nikolas, Bartosch, Natalie, Peschel, Christian, Engh, Richard A., Duyster, Justus
Publicado em 2011

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius

Por Hopfner, Karl-Peter, Eichinger, Andreas, Engh, Richard A., Laue, Frank, Ankenbauer, Waltraud, Huber, Robert, Angerer, Bernhard
Publicado em 1999

The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5

Por Żesławski, Wojciech, Beisel, Hans-Georg, Kamionka, Mariusz, Kalus, Wenzel, Engh, Richard A., Huber, Robert, Lang, Kurt, Holak, Tad A.
Publicado em 2001

Perspective on Computational and Structural Aspects of Kinase Discovery from IPK2014

Por Martin, Eric, Knapp, Stefan, Engh, Richard A., Moebitz, Henrik, Varin, Thibault, Roux, Benoit, Meiler, Jens, Berdini, Valerio, Baumann, Alexander, Vieth, Michal
Publicado no Biochim Biophys Acta (2015)

Inhibition of Aurora Kinase B Is Important for Biologic Activity of the Dual Inhibitors of BCR-ABL and Aurora Kinases R763/AS703569 and PHA-739358 in BCR-ABL Transformed Cells

Por Illert, Anna L., Seitz, Anna K., Rummelt, Christoph, Kreutmair, Stefanie, Engh, Richard A., Goodstal, Samantha, Peschel, Christian, Duyster, Justus, von Bubnoff, Nikolas
Publicado no PLoS One (2014)

Two SnRK2-Interacting Calcium Sensor Isoforms Negatively Regulate SnRK2 Activity by Different Mechanisms

Por Tarnowski, Krzysztof, Klimecka, Maria, Ciesielski, Arkadiusz, Goch, Grażyna, Kulik, Anna, Fedak, Halina, Poznański, Jarosław, Lichocka, Małgorzata, Pierechod, Marcin, Engh, Richard A., Dadlez, Michał, Dobrowolska, Grażyna, Bucholc, Maria
Publicado no Plant Physiol (2020)

The extracellular human melanoma inhibitory activity (MIA) protein adopts an SH3 domain-like fold

Por Stoll, Raphael, Renner, Christian, Zweckstetter, Markus, Brüggert, Michael, Ambrosius, Dorothee, Palme, Stefan, Engh, Richard A., Golob, Michaela, Breibach, Ines, Buettner, Reinhard, Voelter, Wolfgang, Holak, Tad A., Bosserhoff, Anja-Katrin
Publicado em 2001