The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

Enzymes from the histone deacetylase (HDAC) family are highly regulated by different mechanisms. However, only very limited knowledge exists about the regulation of HDAC8, an established target in multiple types of cancer. A previous dedicated study of HDAC class I enzymes identified no redox-sensit...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174833/
https://ncbi.nlm.nih.gov/pubmed/30292946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.013
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