The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

Enzymes from the histone deacetylase (HDAC) family are highly regulated by different mechanisms. However, only very limited knowledge exists about the regulation of HDAC8, an established target in multiple types of cancer. A previous dedicated study of HDAC class I enzymes identified no redox-sensit...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Redox Biol
Main Authors: Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174833/
https://ncbi.nlm.nih.gov/pubmed/30292946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.013
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