The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

Enzymes from the histone deacetylase (HDAC) family are highly regulated by different mechanisms. However, only very limited knowledge exists about the regulation of HDAC8, an established target in multiple types of cancer. A previous dedicated study of HDAC class I enzymes identified no redox-sensit...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174833/
https://ncbi.nlm.nih.gov/pubmed/30292946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.013
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