Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors

There has been significant interest in the bioactivity of the natural product psammaplin A, most recently as a potent and isoform selective HDAC inhibitor. Here we report our preliminary studies on thioester HDAC inhibitors derived from the active monomeric (thiol) form of psammaplin A, as a means t...

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Detaylı Bibliyografya
Asıl Yazarlar: Baud, Matthias G J, Leiser, Thomas, Petrucci, Vanessa, Gunaratnam, Mekala, Neidle, Stephen, Meyer-Almes, Franz-Josef, Fuchter, Matthew J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Beilstein-Institut 2013
Konular:
Letter
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566764/
https://ncbi.nlm.nih.gov/pubmed/23400330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.11
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