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Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues

The malaria parasite Plasmodium falciparum has at least five putative histone deacetylase (HDAC) enzymes, which have been proposed as new antimalarial drug targets and may play roles in regulating gene transcription, like the better-known and more intensively studied human HDACs (hHDACs). Fourteen n...

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Detalhes bibliográficos
Main Authors: Andrews, K. T., Tran, T. N., Lucke, A. J., Kahnberg, P., Le, G. T., Boyle, G. M., Gardiner, D. L., Skinner-Adams, T. S., Fairlie, D. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292526/
https://ncbi.nlm.nih.gov/pubmed/18212103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00757-07
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