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Synthetic Routes and Biological Evaluation of Largazole and Its Analogues as Potent Histone Deacetylase Inhibitors

Natural products with interesting biological properties and structural diversity have often served as valuable lead drug candidates for the treatment of various human diseases. Largazole, isolated from the marine cyanobacterium Symploca sp. has exhibited potent inhibitory activity against many cance...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Shang, Yao, Hequan, Xu, Jinyi, Jiang, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264525/
https://ncbi.nlm.nih.gov/pubmed/21654576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16064681
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