Miniaturized High-Throughput Fluorescent Assay for Conversion of NAD(P)H to NAD(P)

Por Napper, Andrew D., Sivendran, Sharmila
Publicado no Curr Protoc Chem Biol (2011)

Targeted Drug Discovery for Pediatric Leukemia

Por Napper, Andrew D., Watson, Venita G.
Publicado em 2013

Evaluation of an Orthogonal Pooling Strategy for Rapid High-Throughput Screening of Proteases

Por Motlekar, Nuzhat, Diamond, Scott L., Napper, Andrew D.
Publicado em 2008

Development of a High-Throughput Screening–Compatible Assay for the Discovery of Inhibitors of the AF4-AF9 Interaction Using AlphaScreen Technology

Por Watson, Venita Gresham, Drake, Katherine M., Peng, Yu, Napper, Andrew D.
Publicado em 2013

Parallel High-Throughput Automated Assays to Measure Cell Growth and Beta Galactosidase Reporter Gene Expression in the Yeast Saccharomyces cerevisiae

Por Napper, Andrew D., Motlekar, Nuzhat, de Almeida, Rogerio Alves, Pavitt, Graham D.
Publicado no Curr Protoc Chem Biol (2011)

A Sensitive Luminescent Assay for the Histone Methyltransferase NSD1 and Other SAM-Dependent Enzymes

Por Drake, Katherine M., Watson, Venita G., Kisielewski, Anne, Glynn, Rebecca, Napper, Andrew D.
Publicado em 2014

Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms

Por LaFleur, Michael D., Lucumi, Edinson, Napper, Andrew D., Diamond, Scott L., Lewis, Kim
Publicado em 2011

Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening

Por Moorwood, Catherine, Lozynska, Olga, Suri, Neha, Napper, Andrew D., Diamond, Scott L., Khurana, Tejvir S.
Publicado em 2011

Discovery of Chemical Modulators of a Conserved Translational Control Pathway by Parallel Screening in Yeast

Por Motlekar, Nuzhat, de Almeida, Rogerio Alves, Pavitt, Graham D., Diamond, Scott L., Napper, Andrew D.
Publicado em 2009

Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy

Por Gopalakrishnapillai, Anilkumar, Kolb, E. Anders, Dhanan, Priyanka, Mason, Robert W., Napper, Andrew, Barwe, Sonali P.
Publicado no PLoS One (2015)

Beta-hairpin hydrogels as scaffolds for high-throughput drug discovery in three-dimensional cell culture

Por Worthington, Peter, Drake, Katherine M., Li, Zhiqin, Napper, Andrew D., Pochan, Darrin J., Langhans, Sigrid A.
Publicado no Anal Biochem (2017)

Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening

Por Huang, Fei, Motlekar, Nuzhat A., Burgwin, Chelsea M., Napper, Andrew D., Diamond, Scott L., Mazin, Alexander V.
Publicado em 2011

Design, synthesis and evaluation of inhibitors of cathepsin L: exploiting a unique thiocarbazate chemotype

Por Myers, Michael C., Shah, Parag P., Beavers, Mary Pat, Napper, Andrew D., Diamond, Scott L., Smith, Amos B., Huryn, Donna M.
Publicado em 2008

Identification and Characterization of 3-Substituted Pyrazolyl Esters as Alternate Substrates for Cathepsin B. The Confounding Effects of DTT and Cysteine in Biological Assays

Por Myers, Michael C., Napper, Andrew D., Motlekar, Nuzhat, Shah, Parag P., Chiu, Chun-Hao, Beavers, Mary Pat, Diamond, Scott L., Huryn, Donna M., Smith, Amos B.
Publicado em 2007

Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish

Por Clifton, Justin D., Lucumi, Edinson, Myers, Michael C., Napper, Andrew, Hama, Kotaro, Farber, Steven A., Smith, Amos B., Huryn, Donna M., Diamond, Scott L., Pack, Michael
Publicado em 2010

Cytotoxicity of Zardaverine in Embryonal Rhabdomyosarcoma from a Costello Syndrome Patient

Por Cartledge, Donna M., Robbins, Katherine M., Drake, Katherine M., Sternberg, Rachel, Stabley, Deborah L., Gripp, Karen W., Kolb, E. Anders, Sol-Church, Katia, Napper, Andrew D.
Publicado no Front Oncol (2017)

Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-D-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC)

Por Sivendran, Sharmila, Jones, Victoria, Sun, Dianqing, Wang, Yi, Grzegorzewicz, Anna E., Scherman, Michael S., Napper, Andrew D., McCammon, J. Andrew, Lee, Richard E., Diamond, Scott L., McNeil, Michael
Publicado em 2009

KINETIC CHARACTERIZATION AND MOLECULAR DOCKING OF A NOVEL, POTENT, AND SELECTIVE SLOW-BINDING INHIBITOR OF HUMAN CATHEPSIN L

Por Shah, Parag P., Myers, Michael C., Beavers, Mary Pat, Purvis, Jeremy E., Jing, Huiyan, Grieser, Heather J., Sharlow, Elizabeth R., Napper, Andrew D., Huryn, Donna M., Cooperman, Barry S., Smith, Amos B., Diamond, Scott L.
Publicado em 2008

Discovery of Potent Small-Molecule Inhibitors of Multidrug-Resistant Plasmodium falciparum Using a Novel Miniaturized High-Throughput Luciferase-Based Assay

Por Lucumi, Edinson, Darling, Claire, Jo, Hyunil, Napper, Andrew D., Chandramohanadas, Rajesh, Fisher, Nicholas, Shone, Alison E., Jing, Huiyan, Ward, Stephen A., Biagini, Giancarlo A., DeGrado, William F., Diamond, Scott L., Greenbaum, Doron C.
Publicado em 2010