Discovery of Potent Small-Molecule Inhibitors of Multidrug-Resistant Plasmodium falciparum Using a Novel Miniaturized High-Throughput Luciferase-Based Assay

Malaria is a global health problem that causes significant mortality and morbidity, with more than 1 million deaths per year caused by Plasmodium falciparum. Most antimalarial drugs face decreased efficacy due to the emergence of resistant parasites, which necessitates the discovery of new drugs. To...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lucumi, Edinson, Darling, Claire, Jo, Hyunil, Napper, Andrew D., Chandramohanadas, Rajesh, Fisher, Nicholas, Shone, Alison E., Jing, Huiyan, Ward, Stephen A., Biagini, Giancarlo A., DeGrado, William F., Diamond, Scott L., Greenbaum, Doron C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934977/
https://ncbi.nlm.nih.gov/pubmed/20547797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00431-10
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados